A new study conducted by a Stanford University professor has shown that our circadian rhythm — our body’s inner clock that regulates when and how long we sleep — is “tightly entwined” with blood sugar control. Indeed, the study “shows that daily fluctuations in powerful hormones called glucocorticoids directly synchronize the biological clock as an integral part of our mechanism for regulating blood sugar.”
The study was conducted by senior study author Brian Feldman, MD, PhD, who is an assistant professor of pediatric endocrinology at the Stanford University School of Medicine, and practices at Lucile Packard Children’s Hospital. “The most surprising part of our findings is that our internal biologic rhythms are embedded directly into another pathway, one that is essential to regulate metabolism,” he noted.
According to a press release dated October 5th,
The new findings give the first in vivo evidence of a direct link between glucocorticoid hormones and genes that regulate our biological clock. The research may eventually help doctors reduce disabling side effects of glucocorticoid drugs such as prednisone, Feldman said. The work could also help diabetics control their blood sugar levels and may shed light on why night-shift workers are at risk for obesity and diabetes.
The study will be published online Oct. 5 in Proceedings of the National Academy of Sciences. Feldman worked previously at the University of California-San Francisco, where much of the research was conducted.
Interested? Read the rest of the press release here.
This post was written by admin on October 9, 2009